Jet Kwan built a nanoscale model of Hong Kong's International Commerce Center. The simple model uses 2x4 tiles to achieve the skyscraper but is really effective and recognizable.
Elspeth De Montes built the Milan skyscraper of Bosco Verticale. The "green" residential tower is a redesign of an earlier LEGO version, with many great improvements in the update.
The Primalglimse at Forty, drawn by Archilles Gildo Rizzoli in 1938, inspired Erwin te Kortschot to recreate a 3D model. I'd say the model is pretty well replicated, as you can see from the drawing below.
Sheo. built a great tower with an unusual name. "Nasty Tower" is anything but with its incredible weaving pattern. The technique is achieved by connected vertical stripes to a polygonal core.
Jussi Koskinen's version of the Empire State Building is like the model in the official New York City Skyline, only much larger (and better). The 1/1400 scale model extensively uses grille tiles, as in Jussi's previous model of the Willis Tower.
Tom continued to add to his Micropolis layout by adding two more buildings, both inspired from Chicago architecture. The first building is inspired from the Century Building while the second is inspired from the Consumer Building (both located on S State St). Ironically each of the Micropolis builds is named after the inspiration for the other.
kaz.fuji deserves much more attention of their models. One of my favorites is the large model of the Abenobashi Terminal Building, located in Osaka, Japan.
Greg DiNapoli built an extremely large model of One World Trade Center. The 25,000 piece skyscraper stands 8 feet tall and took 8 months to complete.
ilive built a LEGO version of 30 St Mary Axe, commonly referred to as The Gherkin. The London skyscraper is noted for its curvilinear form and stripped facade.
Fellow contributor Rocco Buttliere designed and built First National Center, located in Oklahoma City and commissioned by Cornerstone Development LLC. The 2500 piece model is constructed in Rocco's quintessential building style, which includes extensive use of offset grille tiles and inverted plates.